The term "toxicity testing" describes a set of tests and methods used to evaluate the possible negative effects on living things of substances such as medications, chemicals, and environmental contaminants. Finding out if a drug is poisonous, what dosage levels could be harmful, and which organs or systems could be impacted are the objectives.. .

- In Vitro Toxicity Analysis
- Immuno Toxicity Analysis
- Genetic Toxicity Analysis
- Chemical Toxicity Analysis

In Vitro Toxicity Assays

Assays for in vitro toxicity are laboratory procedures used to evaluate a substance's possible harmful effects on living cells or tissues that are not part of a living organism. Early phases of drug research, environmental testing, and chemical safety evaluations all depend on these assays.

MTT Assay
Resazurin Reduction Assay
LDH Release Assay
Trypan Blue Exclusion Assay
Assays by Flowcytometry.

 

Immuno Toxicity Analysis

Immunotoxicity analysis refers to the study of the potential toxic effects of substances—such as pharmaceuticals, chemicals, and environmental pollutants—on the immune system.
Cytokine Production Assays
Lymphocyte Proliferation Assay
Antibody Production Assays
Flow Cytometry Analysis
Immuno Fluroscence Assays

 

Genetic Toxicity Analysis

These assays evaluate the potential of a substance to cause genetic damage that could lead to mutations, cancer, or other genetic disorders.
Ames Test: A bacterial assay that tests for mutations in bacterial DNA.
Comet Assay (Single Cell Gel Electrophoresis): Measures DNA strand breaks at the single-cell level, indicating genotoxic effects.
Micronucleus Assay: Detects the formation of micronuclei (small nuclei) due to chromosome damage or mitotic defects...

 

Chemical / Trace  Analysis

Trace analysis refers to the detection and quantification of very small amounts of a substance (often called "traces") in a sample. This type of analysis is crucial in a wide variety of scientific and industrial fields, including environmental monitoring, pharmaceuticals, food safety, forensic science, and materials science.
Analysis by HPLC
Analysis by Gas Chromatography
Analysis by Mass Spectrometry

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